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Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.

Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

A misdiagnosed case of HAIR-AN syndrome led to unnecessary surgeries and highlighted the importance of correct diagnosis and treatment.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.

Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.

Understanding how acne develops in different diseases could lead to new treatments.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Oral contraceptives may cause hair loss in women.

Anti-Müllerian hormone is a specific marker for ovarian issues in women with conditions like PCOS.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.