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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Finasteride may help treat chronic CSC, improving vision.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Minoxidil effectively treats female pattern hair loss.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.