September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
14 citations,
April 2014 in “Medical Clinics of North America” The document concludes that quick referral and appropriate treatments are crucial for managing common skin conditions and preventing permanent damage.
30 citations,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
3 citations,
April 2015 in “American journal of biomedical sciences” Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
1 citations,
April 2024 in “Journal of Pharmaceutical and Pharmacological Sciences” The mouse models are effective for testing new hair loss treatments.
September 2016 in “Springer eBooks” Fat-derived stem cells may help treat skin aging and hair loss.
1 citations,
April 2016 in “Journal of Investigative Dermatology” Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.
25 citations,
June 2014 in “Journal of Endocrinology/Journal of endocrinology” Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
December 2015 in “JAMA Dermatology” Dermatologists can help diagnose endocrine disorders like PCOS and metabolic syndrome by looking at skin symptoms.
71 citations,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
38 citations,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
September 1999 in “The Journal of The British Menopause Society” The document concludes that skin aging in women can be caused by UV exposure and hormonal changes, and treatments like hormone replacement therapy and various skin therapies can help.
12 citations,
October 1995 in “The Journal of Clinical Endocrinology & Metabolism” Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
2 citations,
February 2024 in “International journal of molecular sciences” Gut health affects skin diseases, and probiotics might help.
1 citations,
February 2020 in “Cureus” Women with PCOS are more likely to have skin problems like excessive hair, acne, and hair loss.
3 citations,
January 2020 in “Indian Dermatology Online Journal” Skin problems in patients with polycystic ovarian disease are linked to body weight, blood sugar, and hormone levels.
November 2023 in “ACS Omega” New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.
25 citations,
July 2013 in “Environmental Toxicology and Chemistry” Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
209 citations,
September 2008 in “Dermatologic Therapy” Androgens can both increase and decrease hair growth in different parts of the body.
October 2024 in “Our Dermatology Online” Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.
56 citations,
January 2007 in “Pharmaceutical Development and Technology” Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.
12 citations,
December 2012 in “Current Drug Targets” The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
27 citations,
February 2014 in “Planta Medica” Scutellaria baicalensis extract and baicalin may help prevent hair loss.
9 citations,
August 2000 in “Journal of Periodontal Research” Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
14 citations,
December 2011 in “Archives of Dermatological Research” Phyto-vesicles of β-sitosterol may effectively treat hair loss.
2 citations,
August 2023 in “Pharmaceutics” New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.
May 2004 in “Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease” Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
1 citations,
August 2021 in “Педиатр” Endocrine diseases in children often cause skin changes like dryness, redness, acne, hair loss, and more.
12 citations,
February 1997 in “British Journal of Dermatology” The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.
40 citations,
January 1994 in “Skin Pharmacology and Physiology” Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.