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A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

The estradiol valerate/dienogest oral contraceptive helps with heavy periods, may improve acne and symptoms in PCOS, and doesn't affect sexual function.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Estrogen therapy can reduce skin aging but has cancer risks.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Spironolactone most effective for hirsutism, but has side effects.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Treating excessive hair in women requires a holistic approach, including medical, aesthetic, and emotional support.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.

Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.