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Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Adrenal disorders can cause lasting brain and behavior issues in children.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Finasteride may cause kidney damage.

Hirsutism causes significant psychological distress in women.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Early hormones shape sex-specific differences in rat glands.

The document concludes that effectively managing PCOS requires a multifaceted approach.