research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
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research Red Ginseng Extract Promotes Hair Growth in Cultured Human Hair Follicles
Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
research RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia, and Hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.
research Stem Cell-Derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients
The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
research Chrousos Syndrome: From Molecular Pathogenesis to Therapeutic Management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Idiopathic Hirsutism: Androgen Role and Treatment Options
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research Hormonal Treatment of Acne Vulgaris: An Update
Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
research Studying the Genetic Predisposing Factors in the Pathogenesis of Acne Vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Insulin-Lowering Medications in Polycystic Ovary Syndrome
Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
research Pharmacologic Therapy of Polycystic Ovary Syndrome
The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.
research Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone
Spironolactone may help enlarge a small breast linked to Becker's nevus.
research Expression and Function of Nuclear Receptor Co-Activator 4: Evidence of a Potential Role Independent of Co-Activator Activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research Minoxidil May Suppress Androgen Receptor-Related Functions
Minoxidil can reduce functions related to androgen receptors.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research PCOS: Update and Diagnostic Approach
The document concludes that more research is needed to fully understand the causes of PCOS.
research Lack of Effect of a Spironolactone-Containing Cream on Hair Growth in Hirsute Women
The spironolactone cream did not reduce hair growth in women with hirsutism.
research Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene
Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Alopecia Areata: Immune Function and Treatment Options
The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.
research Nocebo Effect in Dermatology
Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.
research 25 Years of Estrogen Receptor Beta: A Personal Journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review
Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.
research Human-Derived Immortalized Dermal Papilla Cells With Constant Expression of Androgen Receptor
Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
research Androgenetic Alopecia in Gender Minority Patients
AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.
research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research A Comparative In Vivo and In Vitro Evaluation of Hair Growth Potential of Extracts and an Isolate from Petroleum Ether Extract of Cuscuta Reflexa Roxb
Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue
KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
research Organizational Effects of Estrogens and Androgens on Estrogen and Androgen Receptor Expression in Pituitary and Adrenal Glands in Adult Male and Female Rats
Early hormones shape sex-specific differences in rat glands.
research Hair Thickness Growth Effect of Adenosine Complex in Male and Female Patterned Hair Loss via Inhibition of Androgen Receptor Signaling
Adenosine complex helps increase hair thickness and density in hair loss.