research Membrane Androgen Receptors May Mediate Androgen Reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
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research The Therapeutic Use of Androgens in Women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research The Hirsute Woman: Challenges in Evaluation and Management
Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
research Disorders of Hair
The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.
research Androgen Receptor Gene CAG and GGN Polymorphisms in Infertile Nigerian Men
Certain gene variations are not a major cause of male infertility in Nigerian men.
research Androgen Excess: Investigations and Management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research The Polycystic Ovary Syndrome: A Position Statement from the European Society of Endocrinology
The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
research Androgens Protect Against Apolipoprotein E4-Induced Cognitive Deficits
Androgens can help prevent memory problems caused by apoE4.
research Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells
Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
research Management of Endocrine Disease: Hyperandrogenic States in Women - Pitfalls in Laboratory Diagnosis
Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research Insulin Resistance and Elevated Androgen Levels: A Major Cause of Polycystic Ovary Syndrome
Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
research COVID-19 and Sex Differences: Mechanisms and Biomarkers
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Acquired Scalp Alopecia: A Review
Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
research The Pathogenesis and Treatment Progress of Androgenic Alopecia
Future treatments for androgenic alopecia may focus on reactivating hair follicle stem cells and improving drug delivery.
research The Psychology of Hair Loss and Its Implications for Patient Care
Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.
research Obesity and Polycystic Ovary Syndrome
Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research The Clinical Management of Hirsutism
The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
research Hirsutism: From Brazil to a Place Near You
No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.
research Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update
The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization
Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
research Serum Concentrations of Dihydrotestosterone Are Associated With Symptoms of Hypogonadism in Biochemically Eugonadal Men
Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.
research Unveiling the Nuances of Adult Female Acne: A Comprehensive Exploration of Epidemiology, Treatment Modalities, Dermocosmetics, and the Menopausal Influence
Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.
research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome
Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
research Polycystic Ovarian Syndrome: Comprehensive Overview and Management Approaches
Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.