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TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.

Early hormones shape sex-specific differences in rat glands.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

A postmenopausal woman's increased male hormone levels were successfully treated with surgery.

The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Persistent radiation-induced hair loss is dose-dependent, and treatments like topical minoxidil can be effective.