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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Testosterone may slow down wound healing and increase inflammation.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.

Female pattern hair loss involves thinning hair on crown and frontal scalp, diagnosed by hair ratio, and treated with minoxidil, antiandrogens, or hair transplantation.

Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Dutasteride works better than finasteride for preventing and treating prostate cancer.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Using finasteride with TIP extends time off period for prostate cancer patients.

Gene differences may affect baldness treatment response in Korean men.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.

Higher DHT in male baldness may protect against prostate cancer.

New compounds may help treat prostate cancer by reducing cell growth.