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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Estrogens and progesterone are key in regulating melasma pigmentation.

Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

miR-195-5p reduces hair growth ability in cells by blocking a specific growth signal.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

D-OCT shows increased blood vessel growth in response to tissue damage in Frontal Fibrosing Alopecia and is useful for diagnosis and monitoring.

Blocking JAK-STAT5 signaling in mice leads to hair growth.

Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.

The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.

All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Sulfotransferase SULT1A1 activity may predict minoxidil treatment success for hair loss.

Gut microbes significantly affect brain steroid levels.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

COVID-19 may worsen hair loss, and Nourkrin® could be a safe treatment option, but more research is needed.

Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.

Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.