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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

The study found no link between baldness patterns and androgen levels in men with benign prostate enlargement or prostate cancer.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

DHT stops hair regrowth in mice, similar to human hair loss.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Early balding at 40 increases prostate cancer risk.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Hsc70 protein may influence hair growth by responding to androgens.

Monascus helps prevent baldness, prostate issues, and may be a natural alternative to medications.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Gene variation affects prostate issues and hair loss.

ROS may affect hair loss related to hormones.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Sebocytes play a key role in controlling androgen levels in human skin.