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    Glossary Androgen-Dependent Diseases

    conditions influenced by male sex hormones like testosterone

    Androgen-Dependent Diseases are medical conditions that are influenced or exacerbated by androgens, which are male sex hormones like testosterone. These diseases include conditions such as androgenetic alopecia (male-pattern baldness), prostate cancer, and polycystic ovary syndrome (PCOS). In these disorders, the presence and activity of androgens play a crucial role in their development and progression.

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    1. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    2. Three cases of androgen‐dependent disease associated with myotonic dystrophy 2003 · 8 citations
    3. Editorial: Androgen-dependent diseases and their treatment Frontiers in Endocrinology · 2024
    4. [Experience in treating androgen-dependent diseases (androgenetic alopecia, acne agminata, hirsutism) with the preparation Diane]. PubMed · 1986
    5. Association of Myo-Inositol and Microlipodispersed Magnesium in Androgen-Dependent Dermatological Diseases: A Retrospective Study Pharmaceuticals · 2025
    6. Genetic Analysis of Androgen Receptors in Development and Disease Advances in pharmacology · 1999 · 44 citations
    7. Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism 2001 · 115 citations
    8. Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development Seminars in reproductive medicine · 2012 · 46 citations
    9. Androgens and Anti-androgen Therapy Archives of Dermatology · 1984 · 30 citations
    10. Role of polymorphism of the androgen receptor gene andnon-random x chromosome inactivation in the pathogenesisof androgenic alopecia Vestnik dermatologii i venerologii · 2010
    11. Non-competitive androgen receptor inhibition in vitro and in vivo Yearbook of Endocrinology · 2010
    12. Biology of the skin and dermatological disease Medicine · 2004 · 7 citations
    13. Alopecia areata incognito: an elusive disease International Journal of Dermatology · 2023
    14. 9 Role of 5α-reductase in health and disease Baillière's clinical endocrinology and metabolism · 1994 · 101 citations
    15. Osteopontin Gene is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner Journal of Investigative Dermatology · 2001 · 17 citations
    16. Abietic Acid from Resina Pini of Pinus Species as a Testosterone 5.ALPHA.-Reductase Inhibitor JOURNAL OF HEALTH SCIENCE · 2010 · 21 citations
    17. 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine Journal of acupuncture and meridian studies · 2010 · 19 citations
    18. Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position Steroids · 1999 · 19 citations
    19. Selective Sensing of Darolutamide and Thalidomide in Pharmaceutical Preparations and in Spiked Biofluids Biosensors · 2022 · 2 citations
    20. Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate Andrologia · 2011 · 2 citations
    21. 5 alpha-reductase inhibition by a new synthetic steroid (PM-9) in cultures of Penicillium crustosum. PubMed · 2002 · 1 citations
    22. Cyproteronacetat zur topischen Therapie androgenabhängiger Erkrankungen 2006
    23. Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications* Endocrine reviews · 1984 · 53 citations
    24. Advances in the treatment of androgenetic alopecia International Journal of Dermatology and Venereology · 2013
    25. [Dermatologic indications for anti-androgenic treatment]. PubMed · 1978
    26. Assessment of efficacy and safety of dapsone gel 5% in the treatment of acne vulgaris مجله كليه طب الكندي · 2019 · 1 citations
    27. Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands Pharmaceutical Sciences · 2021
    28. In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands Current Enzyme Inhibition · 2020
    29. Acne-associated syndromes: models for better understanding of acne pathogenesis Journal of The European Academy of Dermatology and Venereology · 2010 · 99 citations
    30. Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels Recent Patents on Endocrine, Metabolic & Immune Drug Discovery · 2007 · 20 citations