8 citations,
December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
4 citations,
December 2022 in “Frontiers in Endocrinology” Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
2 citations,
January 2023 in “International Journal of Biological Sciences” A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
2 citations,
June 2022 in “Molecules” Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
2 citations,
January 2017 in “Endocrinology” Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
1 citations,
November 2022 in “International Journal of Molecular Sciences” Kelulut Honey can help regulate sex hormone receptors in rats with Polycystic Ovary Syndrome, similar to common medications.
September 2024 in “International Journal of Molecular Sciences” High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
May 2023 in “Experimental Dermatology” Male pattern hair loss may be linked to the developmental origins of hair follicles.
128 citations,
September 2011 in “British Journal of Dermatology” Obesity is linked to various skin problems and may increase the risk of skin cancer.
19 citations,
December 2021 in “Cureus” Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.
66 citations,
February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
6 citations,
November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
1 citations,
April 2016 in “Journal of Investigative Dermatology” Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
11 citations,
January 2015 in “PubMed” A specific laser treatment can promote hair growth in mice by increasing certain protein levels.
3 citations,
January 2022 in “Journal of neuroendocrinology” Sex hormones affect brain cells differently in males and females.
October 2023 in “Scientific Reports” Oxytocin may help hair grow by increasing hair growth-related genes and factors.
January 2022 in “Skin Pharmacology and Physiology” Higher STAT3 levels are found in hair loss areas, but not linked to hair loss severity.
64 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Human stem cells can help form hair follicles in mice.
55 citations,
March 2010 in “Aging” Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
12 citations,
April 2020 in “British Journal of Dermatology” Caffeine may help reduce stress-induced hair loss.
3 citations,
April 2023 in “Frontiers in Pharmacology” ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
3 citations,
January 2023 in “Nutrients” Hordenine may help hair grow by activating a specific cell growth pathway.
July 2023 in “International Journal of Molecular Sciences” N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.
December 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Papulopustular rosacea is an inflammatory skin condition treatable with lifestyle changes and medications.
February 2023 in “Frontiers in Pharmacology” Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
102 citations,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
18 citations,
November 2007 in “Annals of Surgery” Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.