research Modulating Hair Follicle Size with Wnt10b/DKK1 During Hair Regeneration
Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
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research Emerging Treatments in Alopecia
New alopecia treatments aim for better results and fewer side effects.
research Roles of Tumor Suppressors in Regulating Tumor-Associated Inflammation
Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.
research The Efficacy of 24-Month Metformin for Improving Menses, Hormones, and Metabolic Profiles in Polycystic Ovary Syndrome
Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.
research Tissue Engineering Strategies for Human Hair Follicle Regeneration: How Far From a Hairy Goal?
Fully regenerating human hair follicles not yet achieved.
research Changes in Metabolic Profile in Women with a History of PCOS: A Long-Term Follow-Up Study
Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.
research Pharmacological Treatment of Alopecia
Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
research Natural Product Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration
Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.
research The Effect of Glycyrrhizic Acid and Aqueous Licorice Extract on Hair Growth Retardation: In Vitro Mechanistic and Efficacy Studies in Human
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
research Towards a Molecular Understanding of Hair Loss and Its Treatment
Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
research Insulin Resistance and Elevated Androgen Levels: A Major Cause of Polycystic Ovary Syndrome
Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
research Disruption of the Temporally Regulated Cloaca Endodermal β-Catenin Signaling Causes Anorectal Malformations
Disrupting β-catenin signaling in certain cells causes anorectal malformations.
research The Biology of Hair Growth
Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
research A Missense Mutation in Lama3 Causes Androgen Alopecia
A gene mutation in Lama3 is linked to a common type of hair loss.
research Transcriptomic Analysis Reveals Candidate Ligand-Receptor Pairs and Signaling Networks Mediating Intercellular Communication between Hair Matrix Cells and Dermal Papilla Cells from Cashmere Goats
The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.
research Enhancement of Hair Growth Through Stimulation of Dermal Papilla Cells in Human Follicular Dermal
Biofield Energy Healing may increase hair growth by enhancing cell proliferation.
research Preparation of 3H-Labelled Testosterone Metabolites
The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
research Gonadal Sex Steroids: Production, Action, and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research The Effect of Curcumin on Metabolic Parameters and Androgen Level in Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial
Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle
Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.
research Proteomic Analysis of Balding and Non-Balding Mesenchyme-Derived Dermal Papilla Cells from Androgenetic Alopecia Patients Using Online Two-Dimensional Reversed Phase-Reversed Phase LC-MS/MS
Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
research Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway
research Inhibitory Effects of Polyacetylene Compounds from Panax Ginseng on Neurotrophin Receptor-Mediated Hair Growth
Certain compounds from Panax ginseng can block proteins that affect hair growth, potentially helping treat hair loss.
research The Cutaneous Serotoninergic/Melatoninergic System: Securing a Place Under the Sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research TGF-β2 Is Specifically Expressed in Human Dermal Papilla Cells and Modulates Hair Folliculogenesis
TGF-β2 plays a key role in human hair growth and development.
research Microneedles Mediated Bioinspired Lipid Nanocarriers for Targeted Treatment of Alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review
Some plants with flavonoids may help treat hair loss and promote hair growth.
research Hair Pigmentation: A Research Update
Hair color is determined by different melanins and changes with age.