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Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Hair loss needs more research for better treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.