56 citations,
June 2001 in “European journal of cardiovascular prevention & rehabilitation” Early balding linked to higher heart disease risk.
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July 2015 in “Egyptian Journal of Dermatology and Venereology” People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.
90 citations,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
12 citations,
March 2013 in “Gynecological Endocrinology” The study found a significant link between the renin-angiotensin system and insulin resistance in women with polycystic ovary syndrome.
December 2023 in “JCEM case reports” A new gene variant causes glucocorticoid resistance in a mother and son.
5 citations,
May 2017 in “Current Opinion in Pediatrics” Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.
15 citations,
May 2020 in “BMC complementary medicine and therapies” Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
14 citations,
August 2019 in “BioMed Research International” Belly fat is the main predictor of nonalcoholic fatty liver disease in both women with Polycystic ovary syndrome and healthy women.
21 citations,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
23 citations,
May 2019 in “Expert Opinion on Therapeutic Patents” New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
9 citations,
March 2020 in “Gene” Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.
4 citations,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
45 citations,
February 2019 in “Journal of Affective Disorders” Melatonin improved mental health and metabolism in women with PCOS.
129 citations,
January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
July 2023 in “International Journal of Endocrinology” Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
September 2018 in “Fertility and Sterility” African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.
11 citations,
October 2018 in “Hormone and Metabolic Research” Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
60 citations,
February 2013 in “Cell reports” The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
19 citations,
June 2001 in “Annals of Internal Medicine” Tamoxifen can cause total hair loss but its benefits outweigh this side effect.
53 citations,
December 2015 in “JAMA Dermatology” Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.
April 2024 in “International journal of medical science and clinical research studies” Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.
16 citations,
April 2018 in “Current opinion in gynecology and obstetrics” Hispanic women with PCOS are more likely to have liver diseases like NAFLD and NASH.
52 citations,
February 2018 in “Diabetology & Metabolic Syndrome” Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
15 citations,
April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia” Insulin resistance is common in PCOS patients and linked to obesity and increased cardiovascular risk.
4 citations,
February 2019 in “Biological Trace Element Research” Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.
2 citations,
May 2019 in “운동과학” Resistance exercise can reduce muscle protein issues caused by finasteride.
January 2018 in “Elsevier eBooks” The document explains how male reproductive hormones work and affect the body.
4 citations,
January 2018 in “JBRA assisted reproduction” Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
[object Object] 26 citations,
July 2021 in “International journal of adolescent medicine and health” New treatments for PCOS are improving fertility and managing symptoms better.