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The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

The conclusion is that adult males with muscle weakness and hormonal imbalances should be tested for Kennedy's disease.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Hsc70 protein may influence hair growth by responding to androgens.

Hair loss gene linked to prostate issues.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Glioblastoma cells can make androgens, which might help the tumor grow.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Sebocytes play a key role in controlling androgen levels in human skin.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Too much androgen can cause hair loss; finasteride may help.