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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Lowering testosterone speeds up wound healing in male mice.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

High-dose androgen therapy can help manage certain types of androgen resistance.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.

Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Human keratinocytes do not naturally respond to androgens.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

Two gene areas linked to male pattern baldness found, more research needed.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

DHT stops hair regrowth in mice, similar to human hair loss.