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New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Early hormones shape sex-specific differences in rat glands.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Active oxygen scavengers can reverse the suppression of hair cell growth caused by androgens.

Sebocytes play a key role in controlling androgen levels in human skin.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.