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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Germacrone in Curcuma aeruginosa extract degrades at high temperatures but is stable in certain solutions and unaffected by pH levels.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Eating alfalfa sprouts every day can raise testosterone levels in middle-aged men, but broccoli sprouts don't have this effect.

Medications for PCOS don't seem to raise heart disease risk.

Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Lipids are important for healthy hair, but their exact role is not fully understood and needs more research.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.

Microneedles help treat hair loss by improving hair surroundings and promoting growth.

Hair color is determined by different melanins and changes with age.

Solanum nigrum extract may help regrow hair.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Hair follicles are valuable for regenerative medicine and wound healing.

New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.