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Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Two new mutations in the AR gene linked to severe androgen insensitivity were found.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.

Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Anti-androgen therapy might help protect against COVID-19 infection and reduce death risk.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.

Certain herbal compounds might help prevent hair loss in menopausal women by activating Vitamin D receptors.

New acne treatments like clascoterone and minocycline foam are effective, and using antibiotics carefully is important to avoid resistance.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Spironolactone successfully treated hair loss in a 9-year-old girl.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

A gene called BMAL1 plays a role in controlling hair growth.

Analog 23 is a promising compound for prostate cancer treatment.