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Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.

Androgens prevent hair growth by changing Wnt signals in cells.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Adenosine can help treat hair loss by promoting hair growth.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Women with early hair loss have higher blood pressure and aldosterone; screening and treatment may help.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.