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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

A mix of Panax ginseng and bee-pollen may help prevent prostate enlargement in rats.

Certain drugs can worsen hair loss in people prone to androgenetic alopecia.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.

Dutasteride and finasteride affect different cell types differently.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Trazodone might help reverse post finasteride syndrome.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

DHT stops hair regrowth in mice, similar to human hair loss.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Fulvestrant at 10 mg/kg does not promote hair regrowth in dogs with alopecia X.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.