research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
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research Alterations in Androgen Conjugate Levels in Women and Men with Alopecia
Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.
research Androgen Excess Is the Key Element in Polycystic Ovary Syndrome
Too much male hormone is the main cause of Polycystic Ovary Syndrome.
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor
New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.
research Pharmacology of Antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research The Rationale for Physiological Testosterone Replacement in Women
Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
research The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias
Bimatoprost, a glaucoma medication, may also help treat hair loss.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action
Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.