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DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Finasteride helps reduce heart issues and improves heart function.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Testosterone may influence COVID-19 severity and outcomes.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Increased PPARGC1α relates to hair thinning in common baldness.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Mutations in certain receptors can cause diseases and offer new treatment options.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Adenosine complex helps increase hair thickness and density in hair loss.

Chromosomal differences affect how muscle cells respond to testosterone.

Platycladus orientalis leaf extract helps hair grow by activating certain proteins.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Testosterone helps human pancreatic cells increase insulin release.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.