research Quantitative Models for the Study of Hair Growth In Vivo
The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
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research Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain
Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
research Dihydrotestosterone Inhibits Hair Growth in Mice by Inhibiting Insulin-Like Growth Factor-I Production in Dermal Papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research The Double-Edged Sword of Testosterone’s Role in the COVID-19 Pandemic
Testosterone may influence COVID-19 severity and outcomes.
research Becker's Nevus with Ipsilateral Breast Hypoplasia: Improvement with Spironolactone
Spironolactone may help enlarge a small breast linked to Becker's nevus.
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Expression and Function of Nuclear Receptor Co-Activator 4: Evidence of a Potential Role Independent of Co-Activator Activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research Hormonal Activity in Commonly Used Black Hair Care Products: Evaluating Hormone Disruption as a Plausible Contribution to Health Disparities
Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.
research Quality of Life Issues in Male Pattern Hair Loss
Male pattern hair loss negatively affects quality of life, but drug treatments can help.
research Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Relationship Between Betacoronaviruses and the Endocrine System: A New Key to Understand the COVID-19 Pandemic—A Comprehensive Review
Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Advances in Male Hormone Substitution Therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Acne Severity and the Global Acne Grading System in Polycystic Ovary Syndrome
Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Becker Nevus Syndrome
The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.
research Management of Neonates and Children with Male Pseudohermaphroditism
Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Update on the Pathogenesis, Genetics, and Medical Treatment of Patterned Hair Loss
New genetic insights have improved understanding of hair loss, leading to a new test and treatments, but more research is needed on the test and laser comb effectiveness.
research Tamoxifen-Induced Total Alopecia
Tamoxifen can cause total hair loss but its benefits outweigh this side effect.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research Male Androgenetic Alopecia
Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
research Osteopontin Gene Is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner
The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
research Establishment and Characterization of Five Immortalized Human Scalp Dermal Papilla Cell Lines
Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.
research Effects of Lespedeza Cuneata Aqueous Extract on Testosterone-Induced Prostatic Hyperplasia
Lespedeza cuneata extract may help treat enlarged prostate.
research Management of Endocrine Disease: Hyperandrogenic States in Women - Pitfalls in Laboratory Diagnosis
Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
research The Pressing Need for Standardization in Epidemiologic Studies of PCOS Across the Globe
The article concludes that global standardization in PCOS research is crucial for accurate diagnosis and understanding of the condition.
research Association of AR rs6152G/A Gene Polymorphism With Susceptibility to Polycystic Ovary Syndrome in Chinese Women
A certain gene variant may increase the risk of polycystic ovary syndrome in Chinese women.