20 citations,
October 2017 in “Clinical Endocrinology” The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
20 citations,
March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
9 citations,
March 1991 in “Endocrinology” Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
1 citations,
January 1995 in “Journal of Investigative Dermatology” RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.
January 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
16 citations,
April 2007 in “Journal of Obstetrics and Gynaecology Research” Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
27 citations,
September 1999 in “Journal of Investigative Dermatology” Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
305 citations,
February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
197 citations,
January 2019 in “Neuropsychopharmacology” Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
97 citations,
March 2009 in “Dermato-endocrinology” Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
53 citations,
January 2006 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Reduced AR gene methylation may cause early pubic hair growth in girls.
46 citations,
September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
23 citations,
July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
16 citations,
December 2021 in “Frontiers in Endocrinology” Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.
15 citations,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
6 citations,
April 2017 in “JAMA Dermatology” Men's hair loss is not linked to their sex hormone levels, except for lower DHEAS in those with hair loss.
November 2014 in “Elsevier eBooks” Gene mutations can cause problems in male genital development.
January 1998 in “KAGAKU TO SEIBUTSU” The document suggests that male hormones likely affect hair growth and baldness, and future treatments might involve stem cells and androgen-independent cells.
56 citations,
February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
34 citations,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
3 citations,
January 2011 in “Female pelvic medicine & reconstructive surgery” Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
January 2016 in “프로그램북(구 초록집)” Hormones and neuropeptides affect hair growth, with androgens having opposite effects on beard and scalp hair.
25 citations,
November 1979 in “International Journal of Dermatology” Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.
February 1976 in “PubMed” Sex hormone therapy is effective for certain skin conditions like acne and seborrhea, but less so for female hair loss and excessive hair growth.
13 citations,
March 2019 in “Physiological Research” Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.
36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
69 citations,
February 1983 in “Gut” Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.
3 citations,
January 2011 in “International journal of trichology” Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.