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Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.

Tamoxifen can cause total hair loss but its benefits outweigh this side effect.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

DHT stops hair regrowth in mice, similar to human hair loss.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

Smoking is linked to more hair loss and premature graying compared to nonsmokers.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Baldness may lower the risk of testicular cancer.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.

Finasteride doesn't affect ovulation in normal women.

Minoxidil tretinoin liposomal based hydrogel shows promise for effective treatment of hair loss by delivering both drugs at the same time.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.