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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.

South Asian women with PCOS present with different symptoms compared to White women, influenced by ethnicity, obesity, and age.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.