research Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus
Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
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research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Androgenetic Alopecia and Polymorphism of the Androgen Receptor Gene (SNP rs6152) in Patients with Benign Prostate Hyperplasia or Prostate Cancer
Hair loss gene linked to prostate issues.
research Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
research Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium Sativum L.) in HaCaT Cells
Garden cress extract may help treat skin inflammation and androgen-related disorders.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Steroid Sulfatase Inhibitors: Role and Therapeutic Potential
Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.
research Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
research 4th Intercontinental Meeting of Hair Research Societies 2004: The World of Hair
The meeting presented new findings on hair stem cells, pigmentation, genetics, and modern hair treatment techniques.
research The Biology of Hair Growth
Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Anti-Androgenic Effect of Sesquiterpenes Isolated from the Rhizomes of Curcuma Aeruginosa Roxb.
Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.
research Targeting Hirsutism: A New Approach
Eflornithine cream effectively reduces facial hair in women with hirsutism.
research Hidradenitis Suppurativa: An Androgen-Dependent Disorder
Hidradenitis suppurativa improves with antiandrogen therapy.
research Germacrene Analogs Are Anti-Androgenic on Androgen-Dependent Cells
Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Effect of Cuscuta Reflexa Roxb on Androgen-Induced Alopecia
Cuscuta reflexa extract may help treat hair loss caused by hormones.
research Effect of Flutamide and Two Novel Synthetic Steroids on GABA, Glutamine, and Some Oxidative Stress Markers in Rat Brain and Prostate
Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.
research Androgenetic Alopecia, Prostate Volume, And Urinary Symptoms: Is There A Relationship? A Case-Control Study
Hair loss, prostate size, and urinary issues are related due to androgen effects.
research 5α-Reductase Inhibitors: Progress and Therapeutic Potential
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
research Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life
Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
research Male Androgenetic Alopecia
Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Induction of Secreted WNT Factor WISP1/CCN4 by Human Prostate Stromal Cells Under Microenvironmental Hypoxia
Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
research Effect of Petroleum Ether and Ethanol Fractions of Seeds of Abrus Precatorius on Androgenic Alopecia
The seeds of Abrus precatorius, when processed, can prevent hair loss more effectively than common treatments.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.