research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
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research The Diagnosis of Polycystic Ovary Syndrome: The Criteria Are Insufficiently Robust for Clinical Research
The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.
research The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias
Bimatoprost, a glaucoma medication, may also help treat hair loss.
research A Combined Regimen of Cyproterone Acetate and Testosterone Enanthate as a Potentially Highly Effective Male Contraceptive
The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
research Prolonged Treatment with Finasteride (a 5α-Reductase Inhibitor) Does Not Affect Bone Density and Metabolism
Long-term finasteride use doesn't change bone density or metabolism.
research The Biology of Hair Diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research The Safety of 52 Weeks of Oral DHEA Therapy for Postmenopausal Women
Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
research Putative Role for Insulin Resistance in Depression Risk in Polycystic Ovary Syndrome
Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
research Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol
PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.
research Quercetin and Polycystic Ovary Syndrome: Current Evidence and Future Directions - A Systematic Review
Quercetin may help with PCOS symptoms, but more research is needed.
research The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis
South Korean women with hair loss have lower hair density and thickness compared to healthy women.
research Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro
Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
research Hair Loss and Herbs for Treatment
Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
research The Effect of Weight Loss and Treatment with Metformin on Serum Vaspin Levels in Women with Polycystic Ovary Syndrome
Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
research Current Evaluation of Amenorrhea
The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.
research Age-Related Hair Changes in Men: Mechanisms and Management of Alopecia and Graying
Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.
research Testosterone Therapy in Women: Myths and Misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Pathogenesis and Treatment Options for Chemotherapy-Induced Alopecia: A Systematic Review
Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
research Scalp Hair Diameter Increases During Pregnancy
Pregnant women's hair gets thicker.
research Adenosine Increases Anagen Hair Growth And Thick Hairs In Japanese Women With Female Pattern Hair Loss: A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial
Adenosine lotion improves hair growth and thickness in women with hair loss.
research The Lack of Significant Changes in Scalp Hair Follicle Density With Advancing Age
Aging alone barely affects the number of hair follicles, meaning hair loss is minimal without other conditions like androgenetic alopecia.
research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome
Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
research The Effect of 5-Reductase Inhibitors on Erectile Function
5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
research Culture of the Human Pilosebaceous Unit, Hair Follicle, and Sebaceous Gland
The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
research Manifestation of Hyperandrogenism in the Continuous Light Exposure-Induced PCOS Rat Model
Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
research Current Evaluation of Amenorrhea
Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.
research Effects of Finasteride (1 mg) on Hair Transplant
Finasteride improves surrounding scalp hair and increases hair density after hair transplant.
research Endocrine Evaluation of Hirsutism
Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.