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The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Middle-aged women with PCOS often continue to experience symptoms related to high androgen levels, like unwanted hair growth.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

The research found that androgens help control blood flow in the rat prostate through a specific binding site.

The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.

Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Androgens slow hair growth by altering Wnt signaling in balding cells.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

DHT stops hair regrowth in mice, similar to human hair loss.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.