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The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

New method measures finasteride in plasma, finds two formulations bioequivalent.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.

Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.

Skin problems like psoriasis and systemic sclerosis can increase the risk of heart disease, so doctors should watch for heart risks in patients with these conditions.

Mesotherapy is a promising alternative to minoxidil for hair loss with mild side effects.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Zinc can be a helpful secondary treatment for certain skin conditions, but more research is needed to guide its use.

Minoxidil helps hair growth, but results vary.

Pumpkin seed oil may improve prostate health, bladder control, and hair growth in men.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Terbinafine can cause hair loss.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

Minoxidil, when applied to the scalp, can stimulate hair growth but effects vary, stop if treatment ends, and it may cause side effects like fluid retention.

Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.

Oral cyclosporin doesn't stop hair loss.

Microneedling is a promising, simple, and cost-effective treatment for hair loss that works well with other therapies.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Cyclosporin doesn't stop hair loss.

Nanocarrier-based treatments show promise for better hair growth in androgenetic alopecia but need more research.