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The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Finasteride safely lowers DHT levels without affecting testosterone.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.