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Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Chinese women with PCOS have higher androgen levels, which change with age and weight.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Ketoconazole lotion can improve hair regrowth for some people with androgenetic alopecia.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Diagnosing Polycystic Ovary Syndrome is hard due to varying symptoms, no set criteria, and the need for better tests and education.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

Tamoxifen may cause female hair loss by increasing androgen receptor expression.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

ROS may affect hair loss related to hormones.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.