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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Anti-androgens are safe and effective for treating moderate to severe adult female acne.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Androgen deprivation therapy doesn't lower the risk of death from COVID-19 in prostate cancer patients.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

A new compound that could treat various androgen-related conditions was created and analyzed.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

A new compound was made that might help treat diseases related to male hormones.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

No cure for female pattern hair loss, but various effective treatments exist.

The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

Hormones and genes affect hair growth and male baldness.

New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.

Antiandrogen therapy helps treat genetic hair loss.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Spironolactone might cause painful intercourse and decreased sexual arousal in women.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.