research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
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research Dexamethasone, a Synthetic Glucocorticoid, Induces the Activity of Androgen Receptor in Human Dermal Papilla Cells
Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
research Abstract P5-09-21: Selective Androgen Receptor Modulators (SARMs): Enobosarm as Targeted Therapy for the Treatment of Androgen Receptor-Positive Breast Cancer
Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.
research ERG Induces Androgen Receptor-Mediated Regulation of SOX9 in Prostate Cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research The Therapeutic Use of Androgens in Women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Membrane Androgen Receptors May Mediate Androgen Reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research The Rationale for Physiological Testosterone Replacement in Women
Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
research Minoxidil May Suppress Androgen Receptor-Related Functions
Minoxidil can reduce functions related to androgen receptors.
research Treatment of Female Androgenetic Alopecia With Cimetidine
A drug called cimetidine can help treat hair loss in women by blocking androgen receptors. However, it's not the first choice and needs more research.
research Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
research Screening of Synthetic and Natural Product Databases: Identification of Novel Androgens and Antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Uromedic® Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor In Vitro
Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.
research COVID-19, Androgens, and Androgenic Alopecia
COVID-19 may worsen with androgens; anti-androgen drugs could help.
research Global Trends in Research of Androgen Receptor Associated With Breast Cancer From 2011 to 2020: A Scientometric Analysis
Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.
research In Silico Prediction of Metabolites in Petroselinum Crispum for Inhibiting Androgen Receptor as Treatment for Alopecia
Parsley contains compounds that might be good for treating hair loss.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance
Moxibustion may help improve ovarian function by changing androgen levels.
research Treatment Guidelines in Adult Women: Effectiveness of Hormonal Therapy in Treating Acne Vulgaris
Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
research Androgen-Associated and Androgen-Independent Causes of Alopecia and Acne in Women: Literature Review
The document concludes that hair loss and acne in women can be due to both androgen-related and unrelated causes, requiring a collaborative treatment approach.
research Hair Thickness Growth Effect of Adenosine Complex in Male and Female Patterned Hair Loss via Inhibition of Androgen Receptor Signaling
Adenosine complex helps increase hair thickness and density in hair loss.
research Neonatal Inhibition of Androgen Activity Alters the Programming of Body Weight and Orexinergic Peptides Differentially in Male and Female Rats
Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
research Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Repurposing of H1-Receptor Antagonists Cetirizine, Loratadine, and Fexofenadine for Systematic Analysis of ClinicalTrials.gov Trials Using Semi-Automated Processes
Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.
research Summaries of Papers on Dermatological Conditions Conducted in 2008
Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.
research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia
5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.