research The Promoter of an Androgen Dependent Gene in the Hamster Flank Organ
Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.
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research Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia
Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
research Androgen Profile in Chinese Women with Polycystic Ovary Syndrome in Their Reproductive Years
Chinese women with PCOS have higher androgen levels, which change with age and weight.
research Effect of Saw Palmetto Supplements on Androgen-Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth
Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.
research Increased Androgen Receptor Messenger RNA in Frontal-Parietal Hair Follicles of Women with Androgenetic Alopecia
Women with hair loss have more androgen receptors in certain hair follicles.
research Interaction Between Estrogens and Androgen Receptor Genes Microsatellites, Prostate-Specific Antigen, and Androgen Receptor Expressions in Breast Cancer
Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.
research Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
research Additive In Vivo Growth-Inhibitory Effects of Flutamide and Finasteride on Androgen-Sensitive Shionogi 115 Carcinoma
Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
research What Does the Research Say About Androgen Use and Cerebrovascular Events?
Androgen use may increase the risk of stroke, but more research is needed.
research The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males
Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
research Global Trends in Research of Androgen Receptor Associated With Breast Cancer From 2011 to 2020: A Scientometric Analysis
Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.
research Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme
Certain Dibenzo derivatives may help treat prostate cancer.
research Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase
Glioblastoma cells can make androgens, which might help the tumor grow.
research Sexual Function in Women with Androgen Excess Disorders: Classic Forms of Congenital Adrenal Hyperplasia and Polycystic Ovary Syndrome
Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.
research Diagnostic Pitfalls in Ovarian Androgen-Secreting (Leydig Cell) Tumors: Case Series
Ovarian Leydig cell tumors are hard to diagnose with just advanced imaging; expert ultrasound and clinical evaluation are essential.
research Menopausal Androgen Excess-Associated Cardio-Metabolic Risk: Clues for Ovarian Leydig Cell Tumor (Case Report and Mini-Review of Literature)
High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
research Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population
No significant link between CAG repeat numbers and female pattern hair loss in Han Chinese population.
research Female Pattern Hair Loss Possibly Caused by Tamoxifen: Androgen Receptor Expression in the Outer Root Sheath in the Affected Area
Tamoxifen may cause female hair loss by increasing androgen receptor expression.
research Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist
CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
research Relative Binding Affinity of Novel Steroids to Androgen Receptors in Hamster Prostate
New steroids were effective in blocking male hormone receptors in hamster prostates.
research Development of Fluridil, a Topical Suppressor of the Androgen Receptor in Androgenetic Alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Androgenic Alopecia Revealing an Androgen-Secreting Ovarian Tumor
An 80-year-old woman's severe hair loss was caused by a hormone-secreting ovarian tumor.
research Anti-Androgen Therapy in Dermatology: A Review
Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.
research Active Anti-Alopecia Chemical Identification of Merremia Peltata Leaves and Computational Study Toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation
Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.
research Protective Trend of Anti-Androgen Therapy During the COVID-19 Pandemic: A Meta-Analysis
Anti-androgen therapy might help protect against COVID-19 infection and reduce death risk.
research Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations
Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.
research Platelet Factor 4 Inhibits Human Hair Follicle Growth and Promotes Androgen Receptor Expression in Human Dermal Papilla Cells
Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.
research Cortexolone 17α-Propionate (Clascoterone) Is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro
Clascoterone may be an effective topical treatment for hair loss.
research Gender Specificity of a Genetic Variant of Androgen Receptor and Risk of Coronary Artery Disease
A genetic variant in the androgen receptor gene increases heart disease risk in women but not in men.