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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Understanding the mouse hair cycle is crucial for cancer research.

No treatment fully prevents hair loss from chemotherapy yet.

Hair shedding is an active process that could be targeted to treat hair loss.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

CCCA is a hair loss type affecting African women, possibly caused by grooming and chemicals, with various treatments and needing more research.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Advanced human skin models improve drug development and could replace animal testing.

The document concludes that good cosmetic outcomes in hair transplantation depend on the surgeon's artistic skill and careful planning.

Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.

Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Teloptosis is a key point in hair loss that could help in creating prevention-focused hair care strategies.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.

Improved hair loss treatment using special particles and surfactants.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

Nonablative radiofrequency treatments, especially microneedle and fractional types, can improve acne scars by 25%–75% after 3-4 sessions, with full results in 3 months and some side effects.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Use finasteride, minoxidil, and follicular unit transplantation for hair loss treatment.

Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.