January 1997 in “Han-guk hyeonmigyeong hakoeji/Applied microscopy” This study observed that the mechanical connection between hair follicles and connective tissue in human fetal scalp skin is weaker than in the corresponding skin components, reflecting dynamic processes in hair growth.
This study found that the Arabidopsis thaliana protein Formin 2 localizes to plasmodesmata and is crucial for regulating their permeability by anchoring actin filaments, which affects virus susceptibility.
This study found that the protein Formin 2 helps regulate cell-to-cell transport in thale cress by stabilizing actin filaments at plasmodesmata, with its absence leading to increased permeability and vulnerability to viral infections.
7 citations
,
July 2008 in “Experimental Dermatology” This study identified molecular elements controlling the expression and stabilization of THH protein in hair follicle cells, revealing key mechanisms that support hair shaft development in mice.
7 citations
,
February 2016 in “Dermatology and therapy” This study found that t-flavanone may promote hair growth in people with androgenic alopecia by enhancing hair anchoring strength and upregulating desmoglein expression in hair follicles over 30 weeks.
1 citations
,
November 2002 in “Journal of dermatology” This study investigated the histogenetic relationship between basal cell carcinoma and hair follicles, revealing specific staining patterns of a monoclonal antibody in different skin tissues.
95 citations
,
March 2009 in “Differentiation” Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
9 citations
,
November 2020 in “The FASEB journal” This review discusses the role of intermediate filaments in cell signaling and differentiation, emphasizing their impact on stem cell function, development, and disease, but reports no new clinical results.
38 citations
,
November 2020 in “International journal of biochemistry & cell biology” This review discusses the biological roles and diagnostic significance of keratins in mammalian colon epithelial cells and reports no new clinical results.
19 citations
,
July 2011 in “Microscopy and Microanalysis” This article reviews the role of adult stem cells in tissue homeostasis and wound repair, focusing on their regulation within the murine hair follicle's specialized niche, but it presents no new findings.
7 citations
,
April 2012 in “Biomolecular concepts” This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.
42 citations
,
July 2015 in “PLoS ONE” This study presents the first detailed 3D models of the complete K1/K10 keratin dimer and identifies structural features and interactions that may inform understanding of keratin filament assembly.
79 citations
,
August 1998 in “The Journal of Cell Biology” In a transgenic mouse model, this study found that overexpression of keratin 16 in skin keratinocytes led to hyperkeratosis and increased EGF receptor signaling, altering skin cell behavior and structure.
This study explored a mother and daughter with loose anagen hair syndrome linked to wooly hair, identifying an intronic variant in the KRT71 gene that affects hair keratin splicing, thus broadening the spectrum of KRT71-related disorders.
86 citations
,
April 2009 in “Journal of anatomy” This paper reviews the evolution of skin appendages and keratin-associated proteins among amniotes, proposing a model for their genetic divergence without new experimental results.
70 citations
,
January 2014 in “International review of cell and molecular biology” This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.
12 citations
,
December 2023 in “Plant Communications” This study found that long-term exposure to high pH extends root hair elongation by altering actin filament arrangements and vesicle trafficking, but disrupting ADF8/11 function shortens root hairs by affecting these processes.
31 citations
,
December 2010 in “Journal of the American Academy of Dermatology” This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that a low concentration of chitosan induces callose deposition and slows root hair growth in Arabidopsis, suggesting an evolutionary conservation of this response to mild biotic stress across plant types.
36 citations
,
March 2023 in “Bioengineering” This review discusses the development and impact of barbed sutures on surgical outcomes across various procedures but reports no new clinical results.
4 citations
,
January 2013 in “International Journal of Trichology” This study found that the distribution of desmogleins is associated with specific types of keratinization and hair anchorage, as well as hypotrichosis.
This review discusses the cornification process of epidermal keratinocytes in forming the skin barrier and reports no new results; it emphasizes the importance for diagnosis and treatment of skin disorders.
6 citations
,
October 2022 in “Journal of cell science” This study re-analyzed single-cell RNAseq data from human and mouse skin, confirming and refining insights into keratin gene regulation during keratinocyte differentiation in epithelial tissues.
36 citations
,
January 2014 in “Elsevier eBooks” This narrative review discusses the structure and functions of the skin, focusing on its barrier role, self-repair, thermoregulation, and immune functions, and reports no new experimental results.
4 citations
,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
146 citations
,
May 2002 in “The American journal of pathology” This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.
43 citations
,
December 2013 in “Seminars in Cell & Developmental Biology” This mini-review discusses human hair follicle development and summarizes genetic disorders linked to abnormalities in hair follicle morphogenesis, structure, or regeneration, but reports no new experimental results.
33 citations
,
January 2021 in “Aesthetic Surgery Journal” This review suggested that low-level light therapy using red/near-infrared light could be a safe and effective treatment for various skin and hair conditions, though more robust trials are needed to solidify its clinical utility.
27 citations
,
April 2011 in “Folia Histochemica et Cytobiologica” In this study using rats, finasteride-induced DHT deficiency led to morphological changes in seminiferous tubules, linked with altered junctional protein expression, potentially impairing fertility.
23 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.