18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
16 citations,
November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.
11 citations,
June 2017 in “Asian-Australasian journal of animal sciences” Fox genes are important for hair growth and development in cashmere goats.
[object Object] 8 citations,
October 2022 in “Medicina-lithuania” Patients with long COVID after Omicron had fewer hospitalizations and milder symptoms but more fatigue, insomnia, and cough compared to those with Delta.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
4 citations,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.
4 citations,
March 2022 in “BioEssays” Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.
1 citations,
May 2023 in “Cell reports medicine” Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.
1 citations,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
1 citations,
June 2022 in “Journal of Cosmetic Dermatology” Two specific genetic markers increase the risk of hair loss in Asian populations.
1 citations,
January 2022 in “Faculty reviews” The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.
February 2024 in “Epigenomes” Epigenetic mechanisms control skin development by regulating gene expression.
June 2023 in “Journal of Biological Chemistry” Get3d protein helps maintain photosynthesis in plants and photosynthetic bacteria.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
January 2019 in “Our Dermatology Online” Almost 40% of older men in the study had hair loss on the front and side of their legs, and most were unaware of it.
October 2022 in “Hair Transplantation” Latin-Americans experience hair loss and can benefit from hair restoration.
28 citations,
November 2018 in “Journal of structural biology” Different populations have distinct hair structures related to their ancestry.
4 citations,
June 2021 in “Scientific Reports” Hair fiber shape and curvature are not significantly linked when ancestry is considered.
2 citations,
October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The DNA of ancient Koreans from the Three Kingdoms period shows a mix of northern Chinese and Japanese-Jomon ancestry, revealing two distinct genetic groups.
2 citations,
April 2021 in “Journal of The American Academy of Dermatology” Female pattern hair loss affects 32.3% of women, increasing with age and showing no racial differences.
February 2024 in “International Journal of Dermatology” The document concludes that more local research on African skin and hair is needed despite increased scientific output from Sub-Saharan Africa.
49 citations,
March 2014 in “Dermatologic clinics” These skin conditions in African men need combined medical treatments and lifestyle changes.
August 1998 in “Dermatologic Surgery” Use steroid creams without parabens and educate on hair transplant techniques to improve cosmetic surgery outcomes.
2 citations,
May 2021 in “Journal of the Endocrine Society” Men with high genetic risk for Polycystic Ovary Syndrome (PCOS) have increased chances of obesity, type 2 diabetes, heart disease, and hair loss, showing PCOS risk factors can affect both genders.
1 citations,
April 2020 in “medRxiv (Cold Spring Harbor Laboratory)” The study found that Tourette Syndrome may be linked to certain immune system processes and synaptic signaling.
April 2024 in “Human genomics” Identified genes linked to male-pattern baldness may help develop new treatments.
September 2021 in “Physiology News” Increasing research diversity is key for better understanding and treating Parkinson's Disease.
[object Object] 16 citations,
April 2014 in “Dermatologic Clinics” Dermatoscopy helps diagnose hair and scalp disorders in people with Afro-textured hair, but more research is needed for better understanding and treatment.
2 citations,
October 2023 in “Philosophical transactions - Royal Society. Biological sciences” Enzymes that change arginine to citrulline are important for skin barrier and hair formation, and their malfunction can lead to skin conditions and hair disorders.
1 citations,
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Quantifying hair shape is better than using racial categories for understanding hair characteristics.