26 citations,
September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
13 citations,
July 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
6 citations,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
5 citations,
October 2020 in “Lasers in Medical Science” Combination therapy works best for female hair loss, increasing density and thickness.
2 citations,
January 2014 in “Hair therapy & transplantation” New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
January 2024 in “Biomedical journal of scientific & technical research” Vitamins A, B7, C, D, and E are essential for healthy hair growth and preventing damage.
December 2022 in “Deleted Journal” Sheep wool keratin solution safely and effectively promotes hair growth.
October 2022 in “International Journal of Molecular Sciences” The study investigated the effects of fish collagen peptides (CP) on hair growth in human dermal papilla cells and C57BL/6 mice, focusing on the Wnt/β-catenin and BMP signaling pathways. CP significantly enhanced cell proliferation and hair regrowth, with the CP1000 group showing results comparable to finasteride. CP increased the expression of hair growth factors (IGF-1, VEGF, krt27, Gprc5d, Ki67) and decreased TGF-β1, a growth inhibitor. Protein analysis revealed that CP upregulated Wnt10b and β-catenin levels while downregulating BMP4 and BMP6 levels. The findings suggest that CP could be a promising nutraceutical for hair loss prevention and regrowth.
788 citations,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
153 citations,
October 2012 in “Skin Pharmacology and Physiology” Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
113 citations,
June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
86 citations,
July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
49 citations,
January 2010 in “Journal of Investigative Dermatology” Thyroid function affects skin health, with a complex interaction between the two.
26 citations,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
22 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.
15 citations,
October 2017 in “Dermatologic Clinics” New treatments for male hair loss show promise but need more research for safety and effectiveness.
13 citations,
August 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
7 citations,
October 2000 in “Allergo Journal” Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.
5 citations,
September 2020 in “Molecules” Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.
1 citations,
January 2015 in “Journal of clinical and investigative dermatology” IGF-1 from human placenta helps hair grow.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
May 2018 in “Journal of Investigative Dermatology” Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.
April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
1057 citations,
November 2011 in “Annals of Biomedical Engineering” Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.
520 citations,
January 2017 in “AIMS biophysics” Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.