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Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.

Aging causes skin stem cells to work less effectively.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

Oxidative stress contributes to hair graying and loss as we age.

Finasteride effectively treats baldness but may cause sexual side effects.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.