40 citations,
October 2012 in “Dermatologic clinics” More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.
37 citations,
October 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Scalp cooling effectively reduces hair loss from chemotherapy.
34 citations,
June 2005 in “Developmental dynamics” Runx3 helps determine hair shape.
6 citations,
November 2022 in “Journal of autoimmunity” JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
6 citations,
June 2015 in “Journal of theoretical biology” The model showed that immune system guardians and the cytokine interferon-γ are key in alopecia areata progression.
4 citations,
July 2022 in “Annals of translational medicine” Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
3 citations,
January 2021 in “Plastic and Aesthetic Research” Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
1 citations,
July 2017 in “Global journal of pharmacy & pharmaceutical sciences” A new hair loss treatment was created using minoxidil and tretinoin in stable niosomes, which effectively released the drugs over time.
December 2024 in “Veterinary Sciences” This study on Zhexi Angora rabbits used transcriptome sequencing and whole-genome resequencing to explore the genetic factors affecting wool quality. Researchers analyzed 12 rabbits, identifying 182 differentially expressed genes, with 138 upregulated and 44 downregulated in fine-wool rabbits. Key genes such as FRZB, TRIB3, ACE2, and TLR2 were linked to hair follicle development, and pathways like Wnt, TGF-β, and JAK-STAT were enriched. Fine-wool rabbits exhibited higher hair follicle density and finer wool fibers. The study's findings offer valuable insights for molecular breeding programs aimed at enhancing wool quality in Angora rabbits.
August 2024 in “Frontiers in Nutrition” Antioxidant-rich diets may reduce hair loss risk, while pro-inflammatory diets may increase it, especially in women.
August 2024 in “Skin Research and Technology” PRP is an effective and safe treatment for female hair loss.
February 2024 in “Animals” Hair loss peaks in spring and regrowth in late summer, with pregnant females losing the most hair.
January 2024 in “Aging medicine” A COVID-19 infected patient with chronic kidney disease experienced worsened kidney function, hair loss, and unexpected wart clearance.
January 2024 in “Annals of dermatology/Annals of Dermatology” Weight loss can cause temporary hair loss, especially in women and older adults.
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
January 2018 in “Journal of translational science” Eating alfalfa sprouts every day can raise testosterone levels in middle-aged men, but broccoli sprouts don't have this effect.
April 2023 in “Journal of Shaheed Suhrawardy Medical College” PRP treatment effectively improves hair density and thickness in people with androgenic alopecia.
Targeting CXXC5 and GSK-3β may help treat male pattern baldness.
September 2022 in “Dermatology and therapy” Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.
July 2022 in “Journal of Investigative Dermatology” PRP may help treat hair loss, but results vary.
April 2022 in “Journal of Investigative Dermatology” Androgenetic alopecia causes hair thinning due to increased androgen activity, treatable with minoxidil and finasteride.
December 2021 in “Cureus” Minoxidil alone is the most cost-effective treatment for male hair loss at a $50,000 threshold.
84 citations,
December 2008 in “Developmental biology” Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
12 citations,
January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
11 citations,
February 2018 in “Oncotarget” Lower SMAD2/3 activation predicts more severe skin cancer.
1 citations,
December 2022 in “Clinical, Cosmetic and Investigational Dermatology” Midscalp hair density and terminal hair percentage are good indicators of female pattern hair loss severity.
41 citations,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
1 citations,
July 2023 in “Cureus” Some treatments for hereditary hair loss are effective but vary in results and side effects; new therapies show promise but need more research.
1 citations,
November 2022 in “Journal of Dermatological Treatment” Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.
December 2024 in “IntechOpen eBooks” Trichoscopy helps diagnose and track alopecia areata by examining specific hair and scalp markers.