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Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Segmental hair analysis can track testosterone over time but needs adjustments for sex, hair color, and washing frequency.

Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.

BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

Endocrine disruptors may cause early hair loss.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Testosterone therapy increases bone density in older men with low testosterone levels.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

Early balding men may have insulin resistance, but lifestyle changes can help.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Hair restoration surgery can lead to swelling, infections, scarring, numbness, hiccups, and poor hair growth.

Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.