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In this study, ethanol discontinuation in Y 1 R / LacZ transgenic mice significantly decreased neuropeptide Y immunoreactivity and increased Y 1 receptor gene expression in the amygdala, with evidence suggesting an important role for the progesterone metabolite 3α,5α‐TH PROG in these changes.

This study focused on the rheology of almond oil at various temperatures and shear rates, using a Brookfield RVDV II I Ultra Rheometer, to evaluate its potential as a biodegradable lubricant.

In this study, acute restraint stress increased Y1 receptor gene expression in the amygdala and PVN of transgenic mice, but this effect was not due to elevated neuroactive steroid concentrations, indicating a potential ligand-induced mechanism.

This study found that changes in the brain concentrations of neuroactive steroids during pregnancy are linked to increased Y 1 receptor gene expression in the medial amygdala of transgenic mice.

This study found that in adolescent male rats, androgens enhance inhibitory avoidance memory, possibly by interacting with androgen receptors in the amygdala and hippocampus.

This study observed that reduced in utero exposure to the neurosteroid allopregnanolone increased anxiety-like behavior in female guinea pigs during the juvenile period without affecting long-term allopregnanolone levels.

This study found that progesterone and its metabolite, allopregnanolone, provided anti-anxiety and anti-depressive effects in female mice, potentially independent of nuclear progestin receptors but requiring 5α-reduction and estradiol's influence on brain-derived neurotrophic factor.

This study elucidated the multi-component and multi-target mechanisms by which TR and Am may provide therapeutic benefits for treating androgenetic alopecia.

In this study, components like vitamin E, β-sitosterol, and linoleic acid in the kernel of Prunus mira Koehne were reported to promote hair growth in mice, possibly through the Wnt/β-catenin pathway.

In this study, researchers found that both direct and witnessed trauma in mice were linked to lower levels of the neurosteroid allopregnanolone, and that boosting neurosteroidogenesis may alleviate PTSD-like symptoms, suggesting potential treatment strategies for PTSD stemming from either trauma type.

This study suggests that 5alpha-dihydroprogesterone could be an effective, non-sedative anticonvulsant for drug-resistant complex partial seizures, as observed in a rat model.

In this study, researchers found that both direct and witnessed trauma in mice are associated with reduced levels of the neurosteroid allopregnanolone, potentially influencing PTSD outcomes, and that treatment with synthetic neurosteroids may mitigate fear responses linked to observed trauma.

This review concludes that anabolic–androgenic steroid abuse may lead to significant neurotoxicity, affecting brain structure, neurotransmitter systems, and increasing the risk of mood disorders and cognitive deficits.

In this study, progesterone showed anticonvulsant effects in mice via a mechanism that is at least partially independent of its metabolism to THP, without significant psychotoxicity.

This review highlights the potential of Asteraceae plants as antidiabetic agents and their beneficial effects on conditions such as cardiovascular disease and liver cirrhosis, suggesting their use as food and nutraceuticals could help manage diabetes.

This study found that estazolam improved PTSD-like behavior deficits in an animal model, which was linked to increased allopregnanolone levels in specific brain regions.

Modern society values both traditional beauty and imperfections, but media pressures lead to more cosmetic enhancements and ethical concerns.

This study observed that acute stress in rats increased neurosteroid levels linked to enhanced GABA(A) receptor function, raising seizure thresholds, while similar effects were seen in mice with deoxycorticosterone administration.

This study found that women with PMS were more likely to use suppression rather than reappraisal for emotion regulation, and increased suppression was linked to higher skin conductance levels in these women.

This article investigates whether finasteride influences adult hippocampal neurogenesis related to depression and reports no new clinical findings; the authors suggest further research on its neurosteroid inhibition.

This paper reviews the growing use of psychotropic drugs in dermatology due to the link between mental states and skin conditions but does not present new clinical findings.

This article reviews the objectives and design of the Rotterdam Study and summarizes key findings across its focus on various diseases, without reporting new experimental results.

This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.

This article reviews the clinical complications and increased mortality risks associated with Cushing's syndrome but does not present new clinical data; it emphasizes the need for prompt treatment to mitigate these risks.

This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.

This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.

This study found that 94% of healthy men reported low libido and 92% reported erectile dysfunction as persistent sexual side effects after using finasteride for male pattern hair loss, with these effects lasting on average 40 months post-discontinuation.

This review discusses recent advancements in understanding and managing congenital adrenal hyperplasia, including improvements in screening, diagnostics, and potential genetic and cell-based treatments, but reports no new clinical findings.