August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in mice, competition for hair follicles guides the organization of follicle-innervating LTMR neurons during early development, with different neuronal subtypes showing varying adaptive responses to increased neuron populations.
30 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that TGase 3 may contribute to hair fiber scaffolding by forming specific isopeptide bonds between keratin intermediate filaments and keratin-associated proteins.
1514 citations
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December 2011 in “Fertility and sterility” This consensus report reviews current knowledge and identifies knowledge gaps concerning the various health aspects of polycystic ovary syndrome, without presenting new clinical findings.
27 citations
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September 2017 in “Journal of Medicinal Food” In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.
20 citations
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June 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found that long-term dutasteride therapy in men with benign prostatic hyperplasia worsened erectile dysfunction, reduced testosterone levels, and increased blood glucose and lipid profile, indicating negative metabolic impacts.
20 citations
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June 2015 in “Hormone Molecular Biology and Clinical Investigation” This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.
13 citations
,
December 2019 in “Nutrients” In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.
3 citations
,
November 2022 in “International journal of molecular sciences” This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.
2 citations
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March 2023 in “Journal of Public Health in Africa” This study reported that using a Nanostructured Lipid Carrier with a combination of beeswax and oleum cacao improved the characteristics of candlenut oil and enhanced hair growth activity in rats.
1 citations
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September 2025 in “Clinical Cosmetic and Investigational Dermatology” This narrative review highlights the potential of autologous adipose mesenchymal stem cell-derived exosomes (AMSCs-Exos) in anti-skin aging, noting their superior biocompatibility and manufacturing advantages while stressing the need for standardized production protocols to overcome existing application challenges.
1 citations
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September 2016 in “Journal of Obstetrics and Gynaecology Research” This study found no significant association between Helicobacter pylori infection and polycystic ovary syndrome in young women, suggesting more research is needed to explore a potential link.
August 2026 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study found that the addition of SPACE peptide significantly enhanced the penetration of amniotic membrane stem cell metabolites in mice, with only very mild irritation observed.
January 1989 in “Side effects of drugs annual” This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.
May 2026 in “Scientific Reports” This study found that kukui nut oil (AMS oil) promotes hair growth in human hair follicle cultures by increasing PGF2α levels and activating Nrf2 signaling, and a human trial confirmed its efficacy in enhancing eyelash growth.
26 citations
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August 2021 in “Medicine” This study found that low levels of SHBG and testosterone were associated with higher mortality in men with severe COVID-19.
March 2026 in “Frontiers in Physiology” This study found no statistically significant protective effect of antioxidant therapy against acute mountain sickness, though results were inconclusive due to limited data and methodological variability.
74 citations
,
January 2011 in “Reproductive Biology and Endocrinology” This study suggests testosterone gel administered for one year to male chronic pain patients receiving morphine may improve sexual function and mental health, despite limited effects on overall pain scores.
4 citations
,
November 2022 in “Frontiers in Immunology” This review discusses the roles of resident macrophages in the liver and lung, emphasizing their unique contributions to maintaining tissue homeostasis and the interface between circulation and external environments, but reports no new findings.
1 citations
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June 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that an Enterobacter isolate demonstrated high resistance to selenate and effective sorption capacity, suggesting potential for bioremediation of selenium-contaminated environments.
September 2018 in “Value in Health” This study found that Cochrane systematic reviews on drug safety had higher methodological quality than non-Cochrane reviews, with the type of review and disease area affecting quality.
Treatments for acute leukaemia lead to high remission rates, but relapses occur, requiring ongoing advancements in care.
18 citations
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October 2013 in “EFSA Journal” The EFSA panel concluded that coriander seed oil is safe for use as a novel food ingredient at the proposed intake levels for healthy adults.
September 2018 in “Epsilon Archive for Student Projects (University of Southampton)” This study found that treatment with Bacillus amyloliquefaciens UCMB5113 significantly increased root hair growth in half of the tested Arabidopsis thaliana accessions.
71 citations
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August 2019 in “The journal of sexual medicine” In this study, transgender adolescents treated with testosterone for a median of 12 months experienced effective virilization, including voice deepening and increased hair growth, but also showed decreased HDL cholesterol and BMD z-scores, and increased hematocrit, with no short-term safety issues reported.
41 citations
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July 2016 in “Radiation Research” This study found that radiation-induced salivary gland dysfunction in mice involves microvascular damage mediated by ceramide and reactive oxygen species, suggesting ROS scavengers could protect salivary function during radiotherapy for head and neck cancer.
19 citations
,
October 2015 in “British Journal of Dermatology” This review reports very low quality evidence for the effectiveness and safety of treatments in extensive resistant alopecia areata and emphasizes the need for high-quality randomized controlled trials.
14 citations
,
January 2018 Lifestyle changes and medical treatments can help manage infertility in women with PCOS.
7 citations
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September 2017 in “Pharmacoepidemiology and Drug Safety” This study observed a strong overall reduction in the use of CPA/EE in the Netherlands, despite similar proportions of users with acne or other hyperandrogenic conditions before and after the referral procedure.
5 citations
,
December 2020 in “Wound Repair and Regeneration” This review discusses the challenges and perspectives of using platelet-rich plasma in burn and wound management, noting that current variability in its composition and application prevents clear conclusions on its effectiveness.
4 citations
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June 2025 in “Cochrane Database of Systematic Reviews” This Cochrane review found no clear superiority among treatments for central serous chorioretinopathy, with low-dose photodynamic therapy, supplements, and eplerenone showing slightly higher probabilities of improving visual acuity, but evidence remains uncertain due to biases and small study sizes.