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    Glossary Amphiregulin

    protein involved in cell growth and tissue repair

    Amphiregulin is a protein that plays a crucial role in cell growth and healing. It binds to the epidermal growth factor receptor (EGFR) on cells, which can stimulate processes like tissue repair and hair growth. In the context of alopecia, understanding amphiregulin's function could help in developing treatments to promote hair regeneration.

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    Research 30 of 160

    1. Amphiregulin in Fibrotic Diseases and Cancer International Journal of Molecular Sciences · 2025 · 4 citations
    2. Amphiregulin in Fibrotic Diseases and Cancer Preprints.org · 2025 · 2 citations
    3. 1496 Transcription factor SOX2-induced amphiregulin inhibits pressure ulcer formation via suppressing oxidative stress after cutaneous ischemia-reperfusion in mice Journal of Investigative Dermatology · 2023
    4. 412 High amphiregulin expression is a high-risk feature of acute graft-versus-host disease of the skin Journal of Investigative Dermatology · 2018
    5. Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration Frontiers in Immunology · 2018 · 188 citations
    6. Tregs: Where We Are and What Comes Next? Frontiers in Immunology · 2017 · 130 citations
    7. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    8. KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin Development · 2009 · 82 citations
    9. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    10. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015 · 17 citations
    11. Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes Frontiers in Immunology · 2021 · 9 citations
    12. Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice Journal of cell science · 2023 · 2 citations
    13. Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid PloS one · 2017 · 2 citations
    14. Treg–tissue cell interactions in repair and regeneration 2024
    15. 854 Dermal fibroblasts enhance growth factors production by androgens, and modulate keratinocyte proliferation and differentiation 2018
    16. 876 Manipulation of stem cell divisional behavior: Selectively promoting asymmetric and symmetric keratinocyte divisions in vitro Journal of Investigative Dermatology · 2017
    17. 415 IL-17C: Checkpoint in innate skin immunology Journal of Investigative Dermatology · 2018
    18. 413 DC-HIL+ myeloid-derived suppressor cells are elevated in the peripheral blood and lesional skin of cutaneous lupus patients Journal of Investigative Dermatology · 2018
    19. Immune modulation of hair follicle regeneration npj Regenerative Medicine · 2020 · 29 citations
    20. Microarray analysis of androgenetic and senescent alopecia: Comparison of gene expression shows two distinct profiles Journal of Dermatological Science · 2013 · 27 citations
    21. Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development Molecular Biology of the Cell · 2018 · 25 citations
    22. A Review: Proteins Involved in the Major Symptoms of Polycystic Ovarian Syndrome International Journal of Health Sciences (IJHS) · 2022
    23. 410 Oral dysbiosis in palmoplantar pustulosis patients with arthro-osteosis Journal of Investigative Dermatology · 2018
    24. 414 A fitst-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and fluorescence contrast in skin cancer Journal of Investigative Dermatology · 2018
    25. Defining stem cell dynamics and migration during wound healing in mouse skin epidermis Nature Communications · 2017 · 363 citations
    26. Molecular biology of hair morphogenesis: Development and cycling Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution · 2003 · 155 citations
    27. The Immune Functions of Keratinocytes in Skin Wound Healing International Journal of Molecular Sciences · 2020 · 147 citations
    28. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled EMBO journal · 2002 · 127 citations
    29. Regulatory T Cells: the Many Faces of Foxp3 Journal of Clinical Immunology · 2019 · 125 citations
    30. Regulatory T cells in skin Immunology · 2017 · 110 citations