research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
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research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research Non-Edg Family LPA Receptors: The Cutting Edge of LPA Research
New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
research Platelet-Derived Growth Factor Regulates the Proliferation and Differentiation of Human Melanocytes in a Differentiation-Stage-Specific Manner
PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Epimedium Brevicornum Maxim Extract Enhances Melanin Biosynthesis and Melanosome Biogenesis/Transfer
Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
research Aberrant Inflammasome Activation as a Driving Force of Human Autoimmune Skin Disease
Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
research Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect
Minoxidil helps hair growth by activating the β-catenin pathway.
research In Vitro Effects of the Phytocomplex TrichoTech on Human Fibroblasts: Proliferative Potential and Effects on Gene Expression of FGF-7 and FGF-10
TrichoTech™ may help hair growth and skin repair by increasing fibroblast growth and activity.
research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth
Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
research Prostaglandin-Induced Hair Growth
Latanoprost can make eyelashes longer, thicker, and darker.
research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells
Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
research Effect of Hataedock Treatment on Epidermal Structure Maintenance Through Intervention in the Endocannabinoid System
Hataedock treatment improved skin health and reduced atopic dermatitis symptoms by enhancing the skin barrier and reducing inflammation.
research Ectopic Olfactory Receptors in Humans: New Therapeutic Possibilities
Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.
research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
research Successful Treatment of Epidermal Growth Factor Receptor Inhibitor-Induced Alopecia with Doxycycline
Doxycycline can effectively treat hair loss caused by EGFR inhibitors.
research Understanding the Role of Prostaglandin E2 in Regulating Human Platelet Activity in Health and Disease
Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
research Finasteride, a 5α-Reductase Inhibitor, Potentiates Antinociceptive Effects of Morphine, Prevents the Development of Morphine Tolerance and Attenuates Abstinence Behavior in the Rat
Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
research Androgen Receptor: A Promising Therapeutic Target in Breast Cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Redefining Hormone Resistance in Prostate Cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.