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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Zinc is crucial for growth and health in rats.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Testosterone improves mood and thinking skills; finasteride has no effect.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.

A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Pathologic tissues have more soluble proteins than normal tissues.

The study found that a polymer treatment changes the charge on hair surfaces, making bleached hair smoother and less porous.

Yeast grown on wood sugar with added methionine could be a cheap alternative to animal protein for feed.

Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.

A new method was developed to make finasteride for treating hair loss.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.